It is also a useful emulsifier for wateroil systems. It is also used as carrier for sodium stearate and sodium aluminium hydroxylactate in deodorants, perfume and insectrepellent sticks. Lauroglycol fcc is a nonionic waterinsoluble surfactant used as cosurfactant in oral lipidbased formulation sedds and smedds. Usp volatile organic impurities passes usp nf water, wt. National toxicology program technical report series511, 6260. Ep, the food chemicals codex fcc, the chinese food.
In addition to effective articles, this index may also include items recently omitted from the fcc in the indicated book or supplement. Product monograph pr stieprox ciclopirox olamine shampoo 1. Dekol disperse sns has a very pronounced soaping effect in the. Ir spectra passes usp propylene glycol, area % by gas chromatography 99. Ineos oxides produces po at our koeln, germany site, with a high degree of integration into a larger petrochemical site, including a cracker, ineos oxide can ensure a reliable and cost efficient. Identification of the substancemixture and of the companyundertaking date issued 19. Propylene glycol is an aliphatic dihydric alcohol with a wide range of applications in the food industry such as an anticaking agent, antioxidant, humectant, flavoring agent, emulsifier, stabilizer, thickener etc. All spectrum chemical nf products, including all nf polyethylene glycol products are manufactured, packaged and stored under current good manufacturing practices cgmp per 21cfr part 211 in fda registered and inspected facilities. Product safety assessment polyglycol pt series products.
The fcc is a compendium of standards used internationally for the. Product safety assessment polyglycol p series polymers. The united states pharmacopeia and the national formulary usp nf food chemicals codex usp dietary supplements compendium usp medicines compendium mc reference standards other resources pharmacopeial forum fcc forum usp dictionary chromatographic columns usp s compendial activities. Propylene glycol usp kosher certified 100% pure food.
Extended implementation and comment period extension for uspnf and fcc publications posted 27mar2020. Honeywell confidential 2016 by honeywell international inc. No freedom from any patent owned by seller or others is to be inferred. Water determination by karl fischer titration agnieszka kossakowska. Butyl glycol ether revision date 03042015 version 1. Disperse sns prevents the deposits of hard water ions and other impurities during the dyeing process of yarn and fabric. Sold by froggys fog and ships from amazon fulfillment.
Safety assessment of alkane diols as used in cosmetics. This solvent is soluble in water and holds hygroscopic properties, meaning it has the ability to attract hard water molecules. Food and drug administration fda under 21 cfr x184. The books homepage helps you explore earths biggest bookstore without ever leaving the comfort of your couch. Propylene glycol, food and flavor ingredient, fema no 2940. A guide to glycols 4 the structural formulas of the propylene glycols commercially produced by dow are.
In all correspondence, refer to your purchase order number, your usp customer number, andor your usp price quote number. A complete discussion of the background and basis of fdas therapeutic equivalence evaluation policy was published in the federal register on january 12, 1979 44 fr 2932. It is labeled an organic compound in chemistry due to its carbon attributes. The usp and the nf usp nf jointly publish a book of public pharmacopeial standards for chemical and biological drug substances, dosage forms, compounded preparations, excipients, medical devices, and dietary supplements. However, specific regulations on the product in the respective countries and for its intended use have to be observed. Monographs in the fcc consist of tests and specifications for identification, assay and. Identification of the substancemixture and of the companyundertaking 1. Usp, meets the requirements of other standards like the european pharmacopeia. You have selected the maximum number of product attributes 3 to compare.
In the 200person ript, pg served as a reference compound for comparison. Propylene glycol uspep according to the w h e n excellence in propylene glycol. Food chemicals codex online fcc 11 description includes more than 1,100 monographs as well as more than 150 general tests and assays, providing procedures frequently cited in monographs, sometimes with acceptance criteria, in order to avoid repetition of this text. It is a viscous colourless liquid which is nearly odourless but possesses a faintly sweet taste. Usps standards for food ingredients can be found in its food chemicals codex fcc. Propylene glycol, fcc is used as a humectant, solvent, and a preservative in food products.
Propylene glycol uspfcc meets the compendial requirements of the united states pharmacopeia usp and the food chemicals codex f. Monopropylene glycol mpg is the largest volume propylene glycol with mpg us pharmacopeia usp also being an important part of our product range. Epa label information clean water act this product does not contain any substances regulated as pollutants pursuant to the clean water act 40 cfr 122. It is an excellent solvent for many organic compounds including steroids. Prepare your order using your companys purchase order or a formal usp price quote from customer service.
Ewgs guide to healthy cleaning dipropylene glycol substance. Its high molecular weight and nearly odorless nature make it a widely used perfume fixative. Usp food chemicals codex 11th edition 1st supplement only book. Benzyl benzoate is widely used in the perfume and pharmaceutical industries. It is an outstanding solubilizer for hexaclorophene, dimethyl phthalate azulene, etc.
The fifth edition will be a welcome update to food technologists, quality control specialists, research investigators, teachers, students, and others involved in the technical aspects of food safety. The fcc and associated reference materials enables you to verify the identity, quality, and purity of the food ingredients you buy and sell, which help to ensure the overall safety and integrity of the food ingredient supply chain. Monographs in the fcc consist of tests and specifications for identification, assay and impurities. Evaluating 1,3propanediol for potential skin effects. Since its first edition in 1966, the food chemicals codex fcc has provided the accepted standards for quality and purity in food chemicals, officially referenced by the u. Using the above properties of flimit one can show that for any free ultra. Polyglycol p series polymers fluentbrand polyglycols revised.
Cosurfactant and solubilizer in topical dosage forms associated with skin penetration enhancement. Additional information about the federal register is available at the national archives and records administration web site. The excess phthalic anhydrids is hydrolyzed and the phthalic acid formed is neutralized with standard volumetric sodium hydroxide solution. The food chemicals codex fcc is a collection of internationally recognized standards for the purity and identity of food ingredients. Uses advised against food, drug, pesticide or biocidal. Sept 2627, 2016 all interested persons are provided 60 days from the above date to comment on this safety assessment and to identify additional. Identification product name propylene glycol cat no.
Product identifier product name ethyl diglycol edg chemical name diethylene glycol monoethyl ether, ethoxy diglycol, 22etoxietoxiethanol reach reg no. Based on the uses for this product, individuals could be exposed through. Here youll find current best sellers in books, new releases in books, deals in books, kindle ebooks, audible audiobooks, and so much more. Revision number 0 safety data sheet issuing date 04dec2012 revision date 04dec2012 this chemical is considered hazardous according to the osha hazard communication standard 2012 29 cfr 1910. The fcc online is available as an individual account structure. Mar 24, 2020 polyglykol 200 usp is used in different liquid pharmaceutical preparations such as drops or fillings for gelatin capsules. Food and drug administration and many agencies in other countries. Astm e202 18 standard test methods for analysis of. It is a valuable resource for authenticating a wide variety of ingredients, including processing aids, preservatives, flavorings, colorants, and nutrients. Dow propylene glycol uspep general description propylene glycol usp ep pg usp ep, referring to the united states and european pharmacopoeias, is a highpurity grade of monopropylene glycol for use in pharmaceutical, food, cosmetic, personal care, flavor and fragrance, plus a variety of other applications. Polyglycol article about polyglycol by the free dictionary. Articles of propylene glycol monolaurate are included as well. Usp 38 the united states pharmacopeia 1nf 33 the national formulary volume 4a by authority of the united states pharmacopeial convention prepared by the council of experts and its expert committees official from may 1, 2015 the designation on the cover of this publication, usp nf 2015, is for ease of identification only. Ups solutions to provide an appropriate level of power protection against different power problems and failures.
The fcc receives international recognition by manufacturers, vendors, and users of food chemicals. Trademarks are owned by or licensed to the gsk group of companies. Methyl glycol usp fcc recommended use laboratory chemicals. Combined compendium of food additive specifications f a o j e c f a m o n o g r a p h s 1 issn 18177077 volume 1 analytical methods, test procedures and laboratory solutions used by and referenced in the food additive speci.
P261 avoid breathing dust fume gas mist vapours spray. Pdo was tested in two separate human ript involving 100 and 200 subjects, respectively. Ewgs guide to healthy cleaning caprylyl glycol substance. Safety data sheet mono ethylene glycol 1 identification of the substancepreparation and companyundertaking application automotive industry. It is the sodium salt of benzoic acid and exists in this form when dissolved in water. Chemically it is classed as a diol and is miscible with a broad range of solvents, including water, acetone, and chloroform. Safety assessment of alkane diols as used in cosmetics status. Propylene glycol uspfcc, fisher chemical fisher scientific. An fcc standard can be used to characterize ingredients used in food. It also has application as a solvent for artificial musks, and as a plasticizer for cellulose acetate, and nitro cellulose.
Polyethylene glycol 3350, usp acts as a lubricant, coating the surfaces in aqueous and nonaqueous environments. Food chemicals codex 7th edition details this book is a compendium of internationally recognized monograph standards and tests for the purity and quality of food ingredients, e. Relative retention packaging and storagepreserve in tight containers. This facility utilizes a proprietary fermentation process to convert the glucose from corn starch into zemea uspfcc 1,3 propanediol. June 5, 2014 the dow chemical company page 3 of 6 exposure potential3,4 polyglycol p series polymers are used in the production of industrial and consumer products. The food chemicals codex fcc is a compendium of internationally recognized standards for determining the purity and quality of food ingredients. We use cookies to provide a better browsing experience. The food chemicals codex fcc in conjunction with usp reference materials enables manufacturers and suppliers to verify the identity, quality, and purity of the food ingredients they buy and sell. The official rules are published and maintained by the government printing office gpo in the federal register. For those tests that use the procedure of another astm test method, that test method should be consulted for additional information on the significance and use of that test.
By accessing and using this website, you agree to our cookies policy. Polyethylene glycol 3350, usp 25322683 po125 spectrum. The second method is the catalytic one, which can proceed at 150 c, in the presence of ion exchange resin, or a small amount of sulphuric acid or alkali. Safety data sheet creation date 19nov2009 revision date 19mar2019 revision number 7 1. It features roughly 1,200 monographs, including foodgrade chemicals, processing aids, foods such as vegetable oils, fructose, whey, and amino acids, flavoring agents, vitamins, and functional food ingredients such as lycopene, olestra, and short chain. Dlalphatocopherol is approved for use as an antioxidant and as a vitamin e source in most countries. Search results for dipropyleneglycol at sigmaaldrich. Index to fcc 11 the following index is for convenience and informational use only and shall not be used for interpretive purposes. A very high dedication to consistent quality and purity governs the entire product supply process for dow propylene glycol uspep. It is a viscous, colorless liquid, which is nearly odorless but possesses. The hydroxy groups present in a test portion are esterified with phthalic anhydride. Propylene glycol is also present in propylene glycol alginate, which is known as e405. Propylene glycol is is often commonly abbreviated as pg usp or pg usp k and sometimes goes by the name monopropylene glycol or mpg. Mono propylene glycol also known as propylene glycol, pg, propan1, 2diol and mpg is a clear, colourless and viscous liquid with a characteristic odour and has the formula c 3 h 8 o.
Should you have any questions, please contact kevin moore, ph. Zemea uspfcc propanediol dupont tate and lyle bio products. The usp grade is produced according to the highest industry standards and tested for compliance with specifications of united states pharmacopeia. Propylene glycol uspfcc, fisher chemical glass bottle. The seven most common grades for chemicals and reagents. Use the product attributes below to configure the comparison table. Dpt laboratories ltd, san antonio, tx 78215, usa 2006 xo004 ketoconazole, usp gel, 2%. The most common process is by the noncatalytic hydrolysis of propylene oxide in a hightemperature and highpressure environment. June 5, 2014 the dow chemical company page 1 of 6 product safety assessment polyglycol pt series products fluent brand polyglycols polyglycol cp k. Safety assessment of fatty acid amidopropyl dimethylamines as. The food chemicals codex fcc is available in print and online formats. It can be produced by reacting sodium hydroxide with benzoic acid. The fcc grade meets the requirements of the food chemical codex indicates and is suitable for all food, beverage and nutritional supplement appli.
The retention time for propylene glycol is 4 min1,2propanediol 57556. Internationally recognized standards to verify identity, quality, and purity of food ingredients. The propylene glycol revision bulletin supersedes the currently official monograph and will be incorporated into the first supplement to the usp 33nf 28 reissue. Propylene glycol is a compound which is generally recognized as safe gras by the u. Ewgs guide to healthy cleaning is a free, searchable online tool providing consumers with safety ratings for common household cleaners. Mono propylene glycol is produced from propylene oxide. Because use conditions and applicable laws may differ from one l ocation to another and may change with time, customer is responsible for. Uspnf is a combination of two compendia, the united states pharmacopeia usp and the national formulary nf. Page 1 of 5 february 17, 2011 continued on next p age section 1.
372 1068 116 415 1127 414 2 214 305 1260 1335 741 74 874 332 1498 811 964 102 240 1040 283 983 1120 377 337 303 579 664 63 995 336 949 1061 516